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Programs
Early Discovery E Disc
Late Discovery L Disc
Lead Optimization L Opt
IND-Enabling IND
Clinical Clin
Oncology
Programs: IBIO-101
Programs: Trop-2 x CD3*
Programs: MUC16
Programs: Target 5
Immuno-Oncology
Programs: EGFRvIII
Programs: CCR8
Programs: Target 8
Immuno-Oncology
Autoimmune
Programs: PD-1
NIAID Partnership
Programs: Lassa Virus

* Developed with EngageTx bispecific platform

iBio’s technology stack is designed to deliver next-generation precision antibodies for difficult targets and modes of action with the potential for high developability and enhanced safety. Powered by machine learning, our platform combines epitope steering, antibody optimization for monoclonal antibodies and CD3 T-cell engager bispecfics, and antibody masking, to overcome key challenges in discovery and development.

Our team of computational biologists and highly skilled drug hunters are engineering antibodies for hard-to-drug targets to support rapid pipeline growth and maturation. We have a pipeline of 8 biologics, primarily focused on immuno-oncology, and also for autoimmune diseases. Driven by our commitment to innovation, we are developing select programs internally while maintaining the flexibility to explore collaborative opportunities through licensing our programs to strategic partners.

We are excited about the potential therapeutic benefits of our proprietary pipeline and are looking for partners who share our passion for bringing innovative treatments to advance healthcare and improve patient lives.

To learn more about our pipeline candidates and potential partnership opportunities, please contact us.

References

  1. Laughlin, R.C. et al. (2019) “Plant‐made E2 glycoprotein single‐dose vaccine protects pigs against classical swine fever.” Plant Biotechnol J. 17(2):410-420.
  2. “Classical Swine Fever Response Plan: The Red Book”. Foreign Animal Disease Preparedness and Response Plan. National Center for Animal Health Emergency Management. United States Department of Agriculture, Animal and Plant Health Inspection Service. March 2013.
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