Plant cells have a sophisticated eukaryotic protein production machinery that readily translates and assembles protein complexes.
Many naturally occurring plant viruses cause the production of VLPs during infection, which makes plant cells a versatile host for the production of recombinant VLPs.
The iBio VLP platform is based on the production of virus-like particles composed of viral core proteins that self-assemble into spherical particles. This type of VLP has one protein component, making the platform:
- Simple by design
- Amenable to production as recombinant protein
- Highly flexible for the display of antigenic peptides
- Rapidly scalable in combination with the FastPharming® System